Enters state: FromKentucky, Wayne County, near Kenova.
Leaves state: Into Virginia, Greenbrier, near White SulphurSprings.
Counties: Wayne Cabell, Putnam, Kanawha, Fayette, Raleigh,Summers, Greenbrier
Major Cities & Towns: Huntington, Charleston, Beckley,Lewisburg
Comments: The major east-west route across West Virginia, I-64was also one of the last major interstate routes completed in theUnited States. The segment from I-77 at Beckley to the US 60interchange at Sam Black Church was not finished until the late1980s. Prior to that, thru traffic had to use mountainous US 60between Sam Black Church and Charleston. I-64 shares the route withI-77 (the West Virginia Turnpike) between Charleston and Beckley.Future plans call for widening the route to three lanes in eachdirection between Huntington and Charleston.

Begins: At I-79,Monongalia County, near Morgantown.
Leaves state: Into Maryland, rural Preston County
Counties: Monongalia, Preston
Major Cities & Towns: Morgantown
Comments: I-68 was originally numbered US 48 and was built asCorridor E of the Appalachian Development Highway System. It wasrenumbered as an interstate route when the portion of US 40 east ofCumberland, Md., was upgraded to limited-access status. This routeconnects I-79 with I-70 and is a thru route for traffic from statesto the west of West Virginia headed for Washington, D.C., and isalso promoted as an alternative route to the PennsylvaniaTurnpike.

Enters state: FromOhio, Ohio County, at Weeling.
Leaves state: Into Pennsylvania, Ohio County, east ofWheeling. Counties: Ohio
Major Cities & Towns: Wheeling
Comments: This major east-west interstate route cuts throughthe northern panhandle of West Virginia on its route from Utah toMaryland. It spawns West Virginia's only three-digit interstate,I-470.

Enters state: FromVirginia, Mercer County, near Bluefield.
Leaves state: Into Ohio, Wood County, near Williamstown.
Counties: Mercer, Raleigh, Fayette, Kanawha, Jackson, Wood
Major Cities & Towns: Bluefield, Princeton, Beckley,Charleston, Ripley, Parkersburg.
Comments: West Virginia's major north-south interstatehighway, I-77 also carries the West Virginia Turnpike from Princetonto Charleston, and I-64 from Beckley to Charleston. The Turnpike wasa two-lane route that predated the interstate system, which wasfinally expanded to full interstate standards in the late1980s.

Begins: At I-77,Charleston.
Leaves state: Into Pennsylvania, Monongalia County, north ofMorgantown.
Counties: Kanawha, Roane, Clay, Braxton, Gilmer, Lewis,Harrison, Marion, Monongalia.
Major Cities & Towns: Charleston, Weston, Clarksburg,Fairmont, Morgantown.
Comments: This route, in conjunction with I-77 and US 19(Appalachian Corridor L), funnels traffic from the Carolinas northinto Pennsylvania and New York. It runs in mostly an east-westdirection through rural territory after springing from I-77 inCharleston, then turns to the north near Sutton. In conjunction withI-64 and I-68, serves as part of a thru route from Kentucky andpoints west to Washington, D.C. and Baltimore.

Enters state: FromVirginia, Berkeley County, south of Martinsburg.
Leaves state: Into Maryland, Berkeley County, north ofMartinsburg.
Counties: Berkeley.
Major Cities & Towns: Martinsburg.
Comments: One of the busiest north-south interstates in theeastern United States slices through the eastern panhandle of WestVirginia. The volume of traffic is such that West Virginia isconsidering adding an additional lane in each direction.

Enters state: FromOhio, Ohio County, at Wheeling.
Ends: At I-70, Ohio County, at Wheeling.
Counties: Ohio.
Major Cities & Towns: Wheeling.
Comments: West Virginia's only three-digit interstate route,I-470 offers thru I-70 traffic a bypass of downtownWheeling.